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History

... as a drug in Japan. 1970s 1990s 2000s 2015 2016 The bioequivalence of synthesized and natural-fermented was proven. Møller et al. demonstrated in 2016 that synthesized vitamin K2 K2VITAL® and...

k2-academy/history/

Cis/Trans

... biological actitvity Commercial Scale Natural-Fermented Manufacturing Process A challenge with a fermentation production process is the fact that MK-7 is just one of the components in the process, and it...

k2-academy/cistrans/

Bioequivalence

... K2VITAL® and fermentation-derived MK- 7 demonstrated equal reduction of inactive osteocalcin (ucOC). In the second trial, a placebo, three K2VITAL® doses (45, 90 or 180 μg) and one dose (90 μg) of natural-fermented...

k2-academy/bioequivalence/

Daily Dosage & Overage

... for vitamin K2 preparations in combination. The Table below lists the overdose recommendations for fermentationderived K2 and K2VITAL® DELTA when combined with co-ingredients such as calcium, magnesium or...

k2-academy/daily-dosage-overage/

Introduction of K2

... in sufficient quantities, so must be obtained through the diet. This includes vitamin K2. Fermented foods are primary sources of vitamin K2. Western diets are deficient in vitamin K2. As such, K2...

k2-academy/introduction-of-k2/#c204

History

...e history of vitamin K2 spans centuries and continents, back to feudal Japan where Samurai warriors consumed a fermented soybean dish called natto. Historical diets probably provided enough K2. Changes in food...

k2-academy/history/#c370

Different Forms of K

... K2 are MK-4 and MK-7. They are found in animal products such as meat, dairy, eggs (mainly MK-4) and fermented food such as cheese, yogurt, and natto, a fermented soybean product (mainly MK-7). Western diets...

k2-academy/different-forms-of-k/#c397

Cis/Trans

... an all-trans vitamin K2 compared to the mixture of cis and trans forms that is created by some fermentation production processes. fileadmin/content/factsheets/4-Cis-Trans/mk7-reference.png left middle 1...

k2-academy/cistrans/#c410

K2 Deficiency

...iets are low in vitamin K2 and there is a vitamin K2 deficiency in all populations Animal products and certain fermented food products such as cheese are the primary sources of vitamin K2. The daily intake of vitamin K2...

k2-academy/k2-deficiency/#c426

Commercial

... first vitamin K2 manufactured by an organic synthesis process, compared to the traditional natural-fermented process. The achievement of synthesis marked the commercial milestone where vitamin K2 could enter...

k2-academy/commercial/#c445
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